We know the end is coming, but pot prohibition is going to have to be undone state by state. Here are the ones least likely to jump on the bandwagon.

Marijuana prohibition in the US is dying, but it isn't going to vanish in one fell swoop. Even if Congress were to repeal federal pot prohibition, state laws criminalizing the plant and its users would still be in effect—at least in some states.

And it's probably a pretty safe bet that Congress isn’t going to act until a good number of states, maybe more than half, have already legalized it. That process is already underway and is likely to gather real momentum by the time election day 2016 is over.

FAYETTEVILLE -- A panel discussion on medical marijuana offered Fayetteville City Attorney Kit Williams a chance to describe his wife's personal story of how the drug helped her while she underwent chemotherapy treatments for cancer.

But the panel at the Arkansas Health Disparities Conference at the University of Arkansas at Fayetteville also gave a Little Rock doctor, David Smith, a chance to express his concerns about the chemicals in marijuana.

Williams said his wife, Emily, suffered greatly from nausea while being treated for lymphoma, a type of cancer.

But once she began using marijuana, "the pain that she had been feeling, the nausea that had been wrecking her system, started going away almost immediately," Williams said.

In what might turn out to be the best April Fools’ Day prank, an awkward marijuana sign came up on a college avenue in Arkansas. The sign, surprisingly, announced the future opening of the first marijuana dispensary in Arkansas inside a building that once housed EZ Mart. So far, no one has claimed responsibility for bringing up the sign and the owner of the building has claimed lack of knowledge about who placed the sign there, but what is clear is that marijuana is illegal in Arkansas as it is at the federal level.

Annual marijuana holiday (4/20)