Chronic Pain: Herbal Cannabis Showed No Serious Adverse Effects After One-Year Use

There is not yet enough clinical evidence suggesting that cannabis is effective for self-management of pain. Some short-duration trials have shown efficacy, whereas other studies have shown little improvement over placebo. Effective or not, however, cannabis continues to be widely used as a self-management strategy by patients with a wide range of symptoms and diseases. A study in The Journal of Pain suggests that such use over a one-year period did not increase patients’ risk of serious adverse events. This was a prospective cohort study in Canada to describe safety issues among subjects with chronic non-cancer pain, with a participant base of 216 individuals with chronic pain. A standardized herbal cannabis product (12.5% THC) was dispensed to eligible subjects for one year. Controls (215) were subjects with chronic pain from the same clinics who were not cannabis users. The median daily cannabis dose was 2.5 grams per day and subjects...

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