Endocannabinoids Could Be Used To Erase Bad Memories

A brain circuit that helps create new memories to erase scary ones has been identified, at least in mice.

The circuit connects two brain regions associated with emotion and decision making, researchers said in a new study. Other studies have suggested that these brain circuits operate very similarly in both humans and rodents.

"It translates across species very effectively," said study co-author Andrew Holmes, a neuroscientist at the National Institute on Alcohol Abuse and Alcoholism and the National Institutes of Health. "Immediately, we've got an idea of what may be going awry in the human brain in those folks who experience [post-traumatic stress disorder] and anxiety."

Perpetual fear

With post-traumatic stress disorder (PTSD), people who have experienced trauma — such as war, sexual assault or a car accident — may associate a trigger, such as a loud noise or a certain smell, with their past terror. This can...

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