Marijuana extract tames debilitating brain seizures without the buzz

In a group of children and young adults with the most intractable forms of epilepsy, a liquid form of marijuana called cannabidiol reduced seizures by more than 50% without causing the drug's usual "high," researchers said.

Natural brain chemical could harsh the high of marijuana

In an open-label study that enrolled 213 people with a dozen types of severe epilepsy, researchers found that cannabidiol, which is taken by mouth, was relatively well tolerated. In all, 12 subjects, or 6%, ceased taking the drug, also known as CBD, because of side effects, which included drowsiness, tiredness, diarrhea and decreased appetite. In a open-label study, patients and researchers know what drug is being tested.

Among the side effects missing from the medicinal extract of marijuana is the buzz that has made marijuana a popular recreational drug for centuries. CBD accounts for as much as 40% of the...

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