WHY CBD IS NOT ENOUGH: THE ENTOURAGE EFFECT
Several states have or are in the process of legalizing cannabis extracts, typically oils, high in cannabidiol (CBD) and very low in THC. Because these medicines lack THC (the cannabinoid in marijuana that produces the euphoric high), conservative politicians have been much more willing to embrace this approach to medical marijuana.
However, there are dozens of other cannabinoids and terpenoids (terpenes) in marijuana that have proven to provide medical benefit. New research is pointing toward a synergistic effect of these miraculous molecules, revealing that an isolated cannabinoid (like CBD) may provide benefit for some patients, but only a small minority. The combination of multiple, or all, cannabinoids may work best medicinally.
According to the National Institutes of Health, the delicate interaction of cannabinoids and terpenoids — sometimes called the “entourage effect” — can be used to treat “pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, [and] fungal...
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