New Alzheimer's Drug to Enter Clinical Trials

A new drug developed at Lancaster University that may help to prevent the early stages of Alzheimer’s disease is to enter clinical trials.

The number of people with dementia is steadily increasing. Currently there are about 850,000 cases in the UK, with numbers expected to reach over a million by 2021. The most common cause of dementia is Alzheimer’s disease. It begins when a protein called beta-amyloid forms senile plaques that start to clump together in the brain, damaging nerve cells and leading to memory loss and confusion.

David Allsop, Professor of Neuroscience, and Dr Mark Taylor, from the Faculty of Health and Medicine, have developed a new drug which in laboratory tests reduces the number of these senile plaques and the amount of brain inflammation and oxidative damage associated with Alzheimer’s disease.

Lancaster University has filed a patent application for the drug, and it will be progressing into clinical...

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