Cannabis-based drug reduces seizures by over 30 percent in children with severe epilepsy

A cannabis-based drug has significantly reduced the number of seizures in children and young adults who are suffering from severe cases of epilepsies and are no longer responding to standard anti-epileptic drugs. The purified cannabinoid called Epidiolex reduced the monthly motor seizures of the patients by 36.5 percent on its initial trial.

The patients, who commonly experience 30 motor seizures a month before the trial, experienced only 15.8 motor seizures in 12 weeks when treated with Epidiolex. Researchers from UCSF Benioff Children's Hospital San Francisco said the drug could lead to a new treatment for young patients with epilepsies that would be more safe and effective.

The trial involved 162 patients aged between one and 30 with intractable epilepsies and have been resistant to most anti-epileptic treatments. Researchers provided Epidiolex to all the patients over a 12-week period.

Epidiolex is delivered in liquid form and the researchers noted that it contains no tetrahydrocannabinol (THC), the...

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