Marijuana Extract Doesn't Reduce Postoperative Nausea and Vomiting

The marijuana extract tetrahydrocannabinol (THC) isn't effective in preventing nausea and vomiting after surgery in patients at high risk of this common complication, reports a study inAnesthesia & Analgesia.

Intravenous THC had a "negligible" effect on postoperative nausea and vomiting (PONV), as well as "unpredictable psychotropic and sedative side effects," according to the clinical trial by Dr. Lorenz G. Theiler and colleagues of University of Bern, Switzerland. At a time of growing interest in the uses of medical marijuana, the results suggest that marijuana compounds (cannabinoids) aren't a good option to prevent PONV.

No Benefit of Medical Marijuana for PONV
The study included patients undergoing surgical procedures (gynecological or breast surgery) associated with a high risk of PONV. Patients were randomly assigned to receive a "relatively high" dose of intravenous THC or an inactive placebo. Both treatments were given toward the end of surgery, before emergence from general anesthesia....

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