The endocannabinoid system has a fundamental role to play in all aspects of female fertility, from initial fecundity, to implantation of the developing embryo into the endometrium, to delivery of endocannabinoids via breast milk. As well as all this, the EC system also has a vital role in the cessation of fertility.

Symptoms of the perimenopause

During the perimenopause, which typically occurs between 45 and 55 years of age, various unpleasant and occasionally debilitating symptoms occur. These symptoms can be roughly divided into three types: vaginal/uterine; other physical; and psychological.

Vaginal/uterine symptoms include vaginal dryness, pain during intercourse, and atrophic vaginitis (a condition whereby the mucous membranes of the vagina, vulva and related tissues become thinner and lose elasticity).

Other physical symptoms include night sweats, heart palpitations, dizziness, headaches, stiffness, back pain, breast pain, urinary incontinence, night sweats, insomnia, and hot flashes. Psychological symptoms include anxiety, depression, lack of focus,...